Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 10/20 | 0.55 |
| ▸ | DRD4 | P21917 | 10/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418509 | 0.89 | GAA (0.61) | GAALMNAALOX12MAPK1CHRM2 | |
| SCHEMBL11349600 | 0.88 | DRD4 (0.55) | GAADRD2DRD4ADRA1DADRA1A | |
| Propylene Oxide SCHEMBL11346439 | 0.82 | GAA (0.55) | GAALMNAALOX12MAPK1CHRM2 | |
| SCHEMBL11356840 | 0.79 | DRD2 (0.43) | GAADRD2DRD4ADRA1DADRA1A | |
| SCHEMBL20879373 | 0.78 | HDAC6 (0.68) | GAAALDH1A1KDM4E | |
| SCHEMBL11351097 | 0.77 | ALDH1A1 (0.65) | GAADRD2DRD4LMNAMAPK1 | |
| SCHEMBL8366931 | 0.76 | CHRM2 (0.59) | GAALMNAMAPK1CHRM2CHRM4 | |
| SCHEMBL11356536 | 0.76 | MAPT (0.55) | GAALMNAMAPK1CHRM2CHRM4 | |
| SCHEMBL16685211 | 0.76 | CHRM2 (0.51) | GAALMNAMAPK1CHRM2CHRM4 | |
| SCHEMBL11354691 | 0.76 | CHRM2 (0.51) | GAALMNAMAPK1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4252716-A | BLUE SHADES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |