Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11347259 | 0.76 | PTPN1 (0.58) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL11347617 | 0.75 | CYP2D6 (0.43) | CNR1CNR2 | |
| SCHEMBL11341978 | 0.75 | PTPN1 (0.60) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL6271344 | 0.75 | ACMSD (0.58) | PTPN1SLC6A9ADORA1 | |
| Hydrochloric Acid SCHEMBL11345123 | 0.74 | CYP2D6 (0.42) | CNR1CNR2 | |
| SCHEMBL11350618 | 0.74 | PTPN1 (0.55) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL11348434 | 0.74 | PTPN1 (0.55) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL11343130 | 0.74 | PTPN1 (0.59) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL11343658 | 0.73 | PTPN1 (0.54) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 | |
| SCHEMBL11351011 | 0.72 | PTPN1 (0.52) | PTPN1PTPN2PTPN6AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4245099-A | ANTIINFLAMMATORY, ANALGESIC, DIURETIC, ANTIPYRETIC AND HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-01-13 | — | — | US | disclosed |