Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 7/20 | 0.58 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.58 |
| ▸ | HNF4A | P41235 | 2/20 | 0.58 |
| ▸ | DHFR | P00374 | 1/20 | 0.58 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.54 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269698 | 0.80 | SLC6A9 (0.62) | MCL1SLC6A9 | |
| SCHEMBL4122910 | 0.79 | CA12 (0.50) | ACMSDALOX5 | |
| SCHEMBL3978477 | 0.79 | KDM4E (0.57) | HPGD | |
| SCHEMBL29002065 | 0.77 | SRD5A2 (0.64) | FASN | |
| SCHEMBL9823872 | 0.76 | ALDH1A1 (0.53) | ACMSDHPGD | |
| SCHEMBL11344604 | 0.75 | PTPN1 (0.49) | SLC6A9ADORA1PTPN1 | |
| SCHEMBL23143193 | 0.75 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRGSTA1 | |
| SCHEMBL9273036 | 0.75 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRGSTA1 | |
| SCHEMBL29759663 | 0.75 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRGSTA1 | |
| SCHEMBL330602 | 0.75 | ACMSD (1.00) | ACMSDMCL1HNF4ADHFRGSTA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100301-A1 | 2-ARYLOXYETHYL GLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | ELI LILLY AND COMPANY (US) | 2005-10-27 | — | — | WO | disclosed |