Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pyrrole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL11388094 | 0.96 | CA1 (0.36) | — | |
| Oxalic Acid SCHEMBL9047749 | 0.89 | OR51E2 (0.30) | — | |
| Pyrrole SCHEMBL1411959 | 0.88 | — | — | |
| Pyrrole SCHEMBL311019 | 0.86 | — | — | |
| Acetic Acid SCHEMBL27669193 | 0.86 | FFAR3 (0.47) | — | |
| Pyrrole SCHEMBL9400589 | 0.86 | — | — | |
| Pyrrole SCHEMBL16344858 | 0.86 | ACHE (0.47) | — | |
| Pyrrole SCHEMBL11388091 | 0.86 | — | — | |
| Pyrrole SCHEMBL28249470 | 0.84 | — | — | |
| Benzene SCHEMBL15919211 | 0.83 | TP53 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000649-B1 | 5-SUBSTITUTED-1,2-DIHYDRO-3H-PYRROLO(1,2-A)PYRROLE-1-CARBONITRILES AND PROCESS FOR THEIR CONVERSION TO THE CORRESPONDING 1-CARBOXYLIC ACIDS | SYNTEX (U.S.A.) INC. (US) | 1981-03-25 | — | — | EP | claimed |
| CN-116444392-B | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-111821006-B | Spinal implant system | 华沙整形外科股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-116444392-A | Polypeptide protein medicine oral absorption promoter and preparation method and application thereof | 中国药科大学 | 2023-07-18 | — | — | CN | disclosed |
| CN-113574059-A | Modified ionic liquids containing a cyclic phosphorus moiety | 诺姆斯科技股份有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-111839699-A | Surgical systems and methods | 华沙整形外科股份有限公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-111821006-A | Spinal implant system and method of use | 华沙整形外科股份有限公司 | 2020-10-27 | — | — | CN | disclosed |
| CN-110248648-A | The application of the cell membrane binding signal factor | 艾维塔生物医学公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-108383736-A | A kind of preparation method for the quaternary ammonium salt that impurity ion content is low | 常州大学 | 2018-08-10 | — | — | CN | disclosed |
| CN-103732613-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-11-30 | — | — | CN | disclosed |
| WO-2015167253-A1 | METHOD FOR SURFACE MODIFYING PANCREATIC ISLET MEMBRANE BY MEANS OF CHITOSAN CATECHOL SYNTHETIC MATERIAL | 서울대학교산학협력단 | 2015-11-05 | — | — | WO | disclosed |
| CN-101983259-B | Apparatus for forming metal thin film and method for forming metal thin film using same | INKTEC CO LTD | 2013-05-01 | — | — | CN | disclosed |
| CN-101983259-A | Apparatus for forming metal thin film and method for forming metal thin film using same | INKTEC CO LTD | 2011-03-02 | — | — | CN | disclosed |
| EP-0024382-A1 | Piperidine derivatives, their preparation and pharmaceutical compositions containing them | af Ekenstam, Bo (SE) | 1981-03-04 | — | — | EP | disclosed |