Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrrole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27669193 | 1.00 | FFAR3 (0.47) | — | |
| Pyrrole SCHEMBL28065784 | 0.97 | FFAR3 (0.44) | — | |
| Pyrrole SCHEMBL28121315 | 0.94 | FFAR3 (0.41) | — | |
| Pyrrole SCHEMBL3807182 | 0.90 | — | — | |
| Piperazine SCHEMBL3548665 | 0.87 | KMT2A (0.40) | — | |
| Pyrrole SCHEMBL11344690 | 0.86 | — | — | |
| Pyridine SCHEMBL28062987 | 0.84 | NAPRT (0.43) | — | |
| Pyrrole SCHEMBL6770118 | 0.84 | — | — | |
| Pyrrole SCHEMBL9980539 | 0.84 | — | — | |
| Oxalic Acid SCHEMBL9047749 | 0.83 | OR51E2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3948275-A1 | DIAGNOSTIC FOR CHILDHOOD RISK OF AUTISM SPECTRUM DISORDER | Arizona Board of Regents on behalf of Arizona State University (US) | 2022-02-09 | — | — | EP | claimed |
| CN-110407989-B | Method for preparing self-polymerization biological material by taking lignocellulose furfural residues as raw materials | 中国科学院大连化学物理研究所 | 2021-10-15 | — | — | CN | claimed |
| WO-2020206444-A1 | DIAGNOSTIC FOR CHILDHOOD RISK OF AUTISM SPECTRUM DISORDER | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2020-10-08 | — | — | WO | claimed |
| CN-107096567-A | The composite catalyst and preparation method of synthesis of propylene glycol | 中国科学院过程工程研究所 | 2017-08-29 | — | — | CN | claimed |
| CN-105617459-A | Preparation method for nano polypyrrole chitin nerve conduit | SUZHOU HEALTH COLLEGE | 2016-06-01 | — | — | CN | claimed |
| US-8329682-B2 | Pyrrolo-nitrogenous heterocyclic derivatives, the preparation and the pharmaceutical use thereof | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2012-12-11 | — | — | US | claimed |
| CN-101307052-B | Method for preparing pyrrole-N-heterocyclic ring derivates and medical application thereof | SHANGHAI HENGRUI PHARM CO LTD | 2011-08-17 | — | — | CN | claimed |
| US-20100075952-A1 | PYRROLO-NITROGENOUS HETEROCYCLIC DERIVATIES,THE PREPARATION AND THE PHARMCETICAL USE THEEOF | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD (CN) | 2010-03-25 | — | — | US | claimed |
| EP-2157093-A1 | PYRROLO-NITROGENOUS HETEROCYCLIC DERIVATIVES, THE PREPARATION AND THE PHARMACEUTICAL USE THEREOF | Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) | 2010-02-24 | — | — | EP | claimed |
| EP-1475370-B1 | OPTICALLY ACTIVE AZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | MITSUI CHEMICALS INC (JP) | 2009-08-05 | — | — | EP | claimed |
| CN-101307052-A | Method for preparing pyrrole-N-heterocyclic ring derivates and medical application thereof | SHANGHAI HENGRUI PHARM CO LTD (CN) | 2008-11-19 | — | — | CN | claimed |
| US-7271185-B2 | Optically active azole derivative and process for producing the same | MITSUI CHEMICALS, INC. (JP) | 2007-09-18 | — | — | US | claimed |
| US-20050085521-A1 | Optically active azole derivative and process for producing the same | MITSUI CHEMICALS, INC. (JP) | 2005-04-21 | — | — | US | claimed |
| EP-1475370-A1 | OPTICALLY ACTIVE AZOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Mitsui Chemicals, Inc. (JP) | 2004-11-10 | — | — | EP | claimed |
| US-4867979-A | NON-STEROIDAL ANTIINFLAMMATORY AND HYDROABSORPTIVE AGENT | RICHARDSON-VICKS INC. (US) | 1989-09-19 | — | — | US | claimed |
| US-4299770-A | Recovery of substituted pyrrole acetate | MALLINCKRODT, INC. (US) | 1981-11-10 | — | — | US | claimed |
| JP-6025305-A | — | — | None | — | — | JP | disclosed |
| JP-52014762-A | — | — | None | — | — | JP | disclosed |
| US-4299770-A | Recovery of substituted pyrrole acetate | MALLINCKRODT, INC. (US) | 1981-11-10 | — | — | US | disclosed |
| JP-S5214762-A | PREPARATION OF SUBSTITUTED PYRROL ACETIC DERIVATIVES | MITSUBISHI PETROCHEM CO LTD | 1977-02-03 | — | — | JP | disclosed |