Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11389357 | 0.87 | KMT2A (0.34) | HPGDMEN1KMT2AMAOBALDH1A1 | |
| SCHEMBL31742092 | 0.73 | MAPT (0.44) | HPGDALDH1A1KDM4ETSHRMAPT | |
| SCHEMBL5149643 | 0.72 | MAPT (0.40) | HPGDMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL13603792 | 0.70 | IDO1 (0.55) | IDO1HPGDMAOBMAOAALDH1A1 | |
| SCHEMBL11353218 | 0.68 | IDO1 (0.41) | IDO1HPGDMEN1KMT2AMAOB | |
| SCHEMBL8762708 | 0.67 | IDO1 (0.67) | IDO1HPGDMAOBMAOALMNA | |
| SCHEMBL11347690 | 0.66 | IDO1 (0.42) | IDO1HPGDMEN1KMT2AMAOB | |
| SCHEMBL11633682 | 0.65 | IDO1 (0.48) | IDO1HPGDMAOBMAOAALDH1A1 | |
| SCHEMBL6507641 | 0.64 | IDO1 (0.57) | IDO1MEN1KMT2AMAOBMAOA | |
| SCHEMBL9503379 | 0.64 | IDO1 (0.61) | IDO1HPGDMAOBMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000002-B1 | TETRAHYDROFURANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1981-08-26 | — | — | EP | disclosed |
| EP-0000002-A1 | Tetrahydrofurane derivatives, processes for their preparation and their use as herbicides | BAYER AG (DE) | 1978-12-20 | — | — | EP | disclosed |