Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31742092 | 0.86 | MAPT (0.44) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL14935736 | 0.74 | MAPT (0.40) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11389357 | 0.73 | KMT2A (0.34) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL12390037 | 0.72 | MAPT (0.43) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL17965538 | 0.72 | MAPT (0.47) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL13992793 | 0.72 | MAPT (0.47) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10288809 | 0.72 | MAPT (0.47) | MAPTTP53CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11344895 | 0.72 | IDO1 (0.41) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL74549 | 0.72 | MAPT (0.44) | MAPTCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL10040365 | 0.72 | MAPT (0.38) | MAPTRIPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247761-B2 | Method for the production of aryl-aryl coupled compounds | MERCK PATENT GMBH (DE) | 2007-07-24 | — | — | US | disclosed |
| CN-1320021-C | Method for the production of aryl-aryl coupled compounds | COVION ORGANIC SEMICONDUCTORS (DE) | 2007-06-06 | — | — | CN | disclosed |
| EP-1537161-B1 | METHOD FOR THE PRODUCTION OF ARYL-ARYL COUPLED COMPOUNDS | COVION ORGANIC SEMICONDUCTORS (DE) | 2006-03-29 | — | — | EP | disclosed |
| US-20060058524-A1 | Method for the production of aryl-aryl coupled compounds | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2006-03-16 | — | — | US | disclosed |
| CN-1705696-A | Method for the production of aryl-aryl coupled compounds | COVION ORGANIC SEMICONDUCTORS (DE) | 2005-12-07 | — | — | CN | disclosed |
| EP-1537161-A1 | METHOD FOR THE PRODUCTION OF ARYL-ARYL COUPLED COMPOUNDS | Covion Organic Semiconductors GmbH (DE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004022626-A1 | METHOD FOR THE PRODUCTION OF ARYL-ARYL COUPLED COMPOUNDS | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2004-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058524-A1 | Method for the production of aryl-aryl coupled compounds | TYR, AHR, ARSA | MAPT 1554/4885TP53 3749/4885CYP3A4 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.