Naphthalene

Naphthalene

SCHEMBL11345152

c1ccc2c(c1)CN2.c1ccc2ccccc2c1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.64
HSD17B10 Q99714 1/20 0.64
GAA P10253 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
HTR5A P47898 2/20 0.48
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HSD17B3 P37058 1/20 0.41
CYP2A6 P11509 1/20 0.40
ALOX12 P18054 1/20 0.40
PARP1 P09874 1/20 0.39
NPC1 O15118 2/20 0.37
AHR P35869 1/20 0.37
PDK2 Q15119 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1828551 0.92
SCHEMBL2041999 0.92
SCHEMBL30668800 0.92
Ammonia Solution, Strong SCHEMBL7208186 0.90
SCHEMBL5740686 0.79 ALOX15 (0.57) ALOX15HSD17B10GAANPSR1HTR5A
Alcohol SCHEMBL7759130 0.79 ALOX15 (0.57) ALOX15HSD17B10GAANPSR1HTR5A
SCHEMBL5193435 0.79 ALOX15 (0.57) ALOX15HSD17B10GAANPSR1HTR5A
SCHEMBL1639814 0.78 ALOX15 (0.68) ALOX15HSD17B10GAANPSR1HTR5A
SCHEMBL2087881 0.78 ALOX15 (1.00) ALOX15HSD17B10GAANPSR1HTR5A
SCHEMBL31546300 0.78 ALOX15 (1.00) ALOX15HSD17B10GAANPSR1HTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113748189-B Lubricating oil composition for transmission, method for producing same, and lubrication method and transmission using same 出光兴产株式会社 2024-02-27 CN disclosed
CN-113748189-A Lubricating oil composition for transmissions, method for producing same, method for lubricating transmission using lubricating oil composition for transmissions, and transmission 出光兴产株式会社 2021-12-03 CN disclosed
US-4279761-A LUBRICANT ADDITIVE CIBA-GEIGY CORPORATION (US) 1981-07-21 US disclosed
US-4244827-A AS STABILIZING ADDITIVES FOR LUBRICANTS CIBA-GEIGY CORPORATION (US) 1981-01-13 US disclosed