Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HK1 | P19367 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31546300 | 1.00 | ALOX15 (1.00) | ALOX15HSD17B10GAANPSR1MEN1 | |
| SCHEMBL1828551 | 0.85 | — | — | |
| SCHEMBL30668800 | 0.85 | — | — | |
| SCHEMBL2041999 | 0.85 | — | — | |
| Ammonia Solution, Strong SCHEMBL7208186 | 0.82 | — | — | |
| SCHEMBL894019 | 0.81 | ALOX15 (0.67) | ALOX15HSD17B10GAANPSR1AHR | |
| SCHEMBL11111017 | 0.81 | ALOX15 (0.67) | ALOX15HSD17B10GAANPSR1MEN1 | |
| SCHEMBL7337925 | 0.81 | ALOX15 (0.67) | ALOX15HSD17B10GAANPSR1MEN1 | |
| SCHEMBL7866841 | 0.81 | ALOX15 (0.67) | ALOX15HSD17B10GAANPSR1MEN1 | |
| SCHEMBL1639814 | 0.81 | ALOX15 (0.68) | ALOX15HSD17B10GAANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | claimed |
| EP-1130017-B1 | Azole derivatives and their use as superoxide radical inhibitors | OTSUKA PHARMA CO LTD (JP) | 2005-06-15 | — | — | EP | claimed |
| US-RE37556-E1 | (ALKOXYPHENYL)THIAZOLE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-19 | — | — | US | claimed |
| EP-1130017-A2 | Azole derivatives and their use as superoxide radical inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-05 | — | — | EP | claimed |
| EP-0934937-A1 | Azole derivatives as superoxide radical inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | claimed |
| US-5643932-A | PREVENTS CELL DAMAGE AFTER ISCHEMIA AND RE-PERFUSION, SUBSTITUTED THIAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | claimed |
| EP-0513387-A1 | ACTIVE OXYGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-19 | — | — | EP | claimed |
| US-11046889-B2 | Polymerizable compound and optically anisotropic body | DIC CORPORATION (JP) | 2021-06-29 | — | — | US | disclosed |
| US-10919870-B2 | Polymerizable compound and optically anisotropic body | DIC CORPORATION (JP) | 2021-02-16 | — | — | US | disclosed |
| US-10649124-B2 | Composition including compound having mesogenic group, polymer and optically anisotropic body obtained by polymerizing polymerizable composition, and phase difference film | DIC CORPORATION (JP) | 2020-05-12 | — | — | US | disclosed |
| US-10633353-B2 | Polymerizable compound, composition, polymer, optically anisotropic body, liquid crystal display element, and organic EL display | DIC CORPORATION (JP) | 2020-04-28 | — | — | US | disclosed |
| US-20190025490-A1 | COMPOSITION INCLUDING COMPOUND HAVING MESOGENIC GROUP, POLYMER AND OPTICALLY ANISOTROPIC BODY OBTAINED BY POLYMERIZING POLYMERIZABLE COMPOSITION, AND PHASE DIFFERENCE FILM | DIC CORPORATION (JP) | 2019-01-24 | — | — | US | disclosed |
| US-20180037817-A1 | POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2018-02-08 | — | — | US | disclosed |
| EP-0640592-A1 | N-acylated tricyclic azaheterorings useful as vasopressin antagonists | AMERICAN CYANAMID COMPANY (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5348965-A | N-substituted azaheterocyclic carboxylic acids | NOVO NORDISK A/S (DK) | 1994-09-20 | — | — | US | disclosed |
| EP-0607864-A2 | Tricyclic condensed heterocyclic compounds for the treatment of senile dementic | Takeda Chemical Industries, Ltd. (JP) | 1994-07-27 | — | — | EP | disclosed |
| EP-0585314-A1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS. | NOVO NORDISK AS (DK) | 1994-03-09 | — | — | EP | disclosed |
| WO-1992020658-A1 | NOVEL HETEROCYCLIC CARBOXYLIC ACIDS | NOVO NORDISK A/S (DK) | 1992-11-26 | — | — | WO | disclosed |
| EP-0513387-A1 | ACTIVE OXYGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-19 | — | — | EP | disclosed |
| US-4230703-A | ANALGESICS; ANTIINFLAMMATORY AGENTS | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10919870-B2 | Polymerizable compound and optically anisotropic body | ZYX, ZW10, DPY30 | ALOX15 1452/4885HSD17B10 1482/4885GAA 2711/4885 |
| US-10633353-B2 | Polymerizable compound, composition, polymer, optically anisotropic body, liquid crystal display element, and organic EL display | RPL19, RPL24, RPL29 | ALOX15 88/4885HSD17B10 2555/4885GAA 2314/4885 |
| US-11046889-B2 | Polymerizable compound and optically anisotropic body | OCIAD1, RCC1, OCIAD2 | ALOX15 26/4885HSD17B10 1339/4885GAA 3881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.