Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 2/20 | 0.49 |
| ▸ | KLK1 | P06870 | 2/20 | 0.49 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.49 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11288797 | 0.84 | HSP90AB1 (0.64) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT | |
| SCHEMBL9867738 | 0.84 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT | |
| SCHEMBL11343595 | 0.81 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT | |
| SCHEMBL10933923 | 0.80 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT | |
| SCHEMBL432204 | 0.80 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT | |
| SCHEMBL11340585 | 0.80 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT | |
| SCHEMBL11347012 | 0.79 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT | |
| SCHEMBL11295395 | 0.79 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT | |
| SCHEMBL10488407 | 0.79 | LMNA (0.79) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT | |
| SCHEMBL11346040 | 0.79 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4245099-A | ANTIINFLAMMATORY, ANALGESIC, DIURETIC, ANTIPYRETIC AND HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1981-01-13 | — | — | US | disclosed |