Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.55 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1122659 | 0.96 | ALDH1A1 (0.58) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28175021 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL28110048 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL3913858 | 0.94 | ALDH1A1 (0.56) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL11345578 | 0.93 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL28774745 | 0.89 | TNF (0.53) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| Boric Acid SCHEMBL28121619 | 0.89 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| SCHEMBL28917948 | 0.89 | ALDH1A1 (0.55) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| Perchlorate SCHEMBL3905341 | 0.88 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2ANPC1RAB9A | |
| Urea SCHEMBL27676499 | 0.86 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306014-A | AMMONIA OR AMINES SUPPRESS THE COLOR-FORMING REACTION SYSTEM | RICOH CO., LTD. (JP) | 1981-12-15 | — | — | US | disclosed |