Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11436261 | 0.95 | CA12 (0.62) | MEN1KMT2AGAAHDAC4HDAC1 | |
| SCHEMBL29048358 | 0.87 | PTPN2 (0.57) | MEN1KMT2AHDAC4HDAC1HDAC8 | |
| SCHEMBL11705580 | 0.87 | MEN1 (0.86) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL11306466 | 0.86 | KMT2A (0.65) | MEN1KMT2AGAAHDAC4HDAC1 | |
| SCHEMBL14912564 | 0.82 | HPGD (0.54) | MEN1KMT2AGAAHDAC8ALDH1A1 | |
| SCHEMBL2005010 | 0.82 | CA12 (0.81) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL92717 | 0.81 | KMT2A (1.00) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL1952693 | 0.81 | KMT2A (1.00) | MEN1KMT2AGAACA12CA1 | |
| SCHEMBL20704786 | 0.81 | CA12 (0.64) | MEN1KMT2AGAAHDAC4HDAC1 | |
| SCHEMBL9479370 | 0.81 | KMT2A (1.00) | MEN1KMT2AGAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298522-A | HEAT AND AGING RESISTANCE | NIPPON ZEON CO. LTD. (JP) | 1981-11-03 | — | — | US | disclosed |