Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.57 |
| ▸ | CES1 | P23141 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264957 | 0.91 | TDP1 (0.70) | PTPN2PTPN1PTPN5CES1MEN1 | |
| SCHEMBL11436261 | 0.91 | CA12 (0.62) | MEN1ALDH1A1KMT2ATDP1CA1 | |
| SCHEMBL15836440 | 0.91 | CA1 (0.63) | PTPN2PTPN1PTPN5MEN1ALDH1A1 | |
| SCHEMBL11673037 | 0.91 | MEN1 (0.67) | PTPN2PTPN1PTPN5MEN1ALDH1A1 | |
| SCHEMBL14409393 | 0.91 | KMT2A (0.67) | PTPN2PTPN1PTPN5MEN1ALDH1A1 | |
| SCHEMBL11306466 | 0.88 | KMT2A (0.65) | PTPN2PTPN1PTPN5MEN1ALDH1A1 | |
| SCHEMBL11345686 | 0.87 | MEN1 (0.68) | MEN1ALDH1A1KMT2ATDP1CA1 | |
| SCHEMBL28050245 | 0.87 | UCHL1 (0.49) | PTPN2PTPN1PTPN5CES1MEN1 | |
| SCHEMBL15836442 | 0.87 | MEN1 (0.53) | PTPN2PTPN1PTPN5MEN1ALDH1A1 | |
| SCHEMBL15836439 | 0.84 | LMNA (0.56) | PTPN2PTPN1PTPN5CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284631-A | Three-dimensional covalent organic framework lithium salt containing cage-shaped silsesquioxane, and preparation method and application thereof | 国科广化韶关新材料研究院 | 2023-06-23 | — | — | CN | disclosed |