Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5612563 | 0.81 | CYP2D6 (0.47) | CYP2D6CYP2C9ALOX15CYP2C19PKM | |
| SCHEMBL11352276 | 0.79 | CYP3A4 (0.43) | CYP2D6CYP2C9ALOX15CYP2C19PKM | |
| SCHEMBL11347599 | 0.79 | CYP2D6 (0.43) | CYP2D6CYP2C9ALOX15CYP2C19PKM | |
| SCHEMBL9499184 | 0.78 | CYP2D6 (0.49) | CYP2D6CYP2C9ALOX15CYP2C19PKM | |
| SCHEMBL13295168 | 0.78 | CYP2D6 (0.67) | CYP2D6CYP2C9ALOX15CYP2C19PKM | |
| SCHEMBL30450086 | 0.76 | CYP2D6 (0.40) | CYP2D6CYP2C9ALOX15CYP2C19PKM | |
| SCHEMBL7861316 | 0.76 | CYP2D6 (0.40) | CYP2D6CYP2C9ALOX15CYP2C19PKM | |
| SCHEMBL28647603 | 0.75 | CYP2D6 (0.52) | CYP2D6CYP2C9ALOX15CYP2C19PKM | |
| SCHEMBL20808843 | 0.75 | CYP2D6 (0.52) | CYP2D6CYP2C9ALOX15CYP2C19PKM | |
| SCHEMBL278233 | 0.75 | CYP2D6 (0.52) | CYP2D6CYP2C9ALOX15CYP2C19PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001910-B1 | PREPARATION OF 4,4'-DIHYDROXY STILBENES OR DERIVATIVES THEREOF | MONSANTO COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| EP-0001909-B1 | PREPARATION OF 1,2-BIS(4-HYDROXYARYL)ETHANES BY ONE-STEP DEHYDROHALOGENATION-REARRANGEMENT-HYDROGENATION OF 1,1-BIS(4-HYDROXYARYL)-2-HALOETHANES, WHICH MAY BE FOLLOWED BY ACYLATION | MONSANTO COMPANY (US) | 1981-08-12 | — | — | EP | disclosed |
| US-4189610-A | Preparation of 4,4-dioxy-substituted stilbenes | MONSANTO COMPANY (US) | 1980-02-19 | — | — | US | disclosed |
| US-4156787-A | HYDROGENATION CATALYST | MONSANTO COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| EP-0001910-A1 | Preparation of 4,4'-dihydroxy stilbenes or derivatives thereof | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |
| EP-0001909-A1 | Preparation of 1,2-bis(4-hydroxyaryl)ethanes by one-step dehydrohalogenation-rearrangement-hydrogenation of 1,1-bis(4-hydroxyaryl)-2-haloethanes, which may be followed by acylation | MONSANTO COMPANY (US) | 1979-05-16 | — | — | EP | disclosed |