Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7861316 | 1.00 | CYP2D6 (0.40) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 | |
| SCHEMBL14268305 | 0.87 | ALOX15 (0.60) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 | |
| SCHEMBL4761848 | 0.85 | LMNA (0.50) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 | |
| SCHEMBL11173027 | 0.82 | ALOX15 (0.40) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 | |
| SCHEMBL12964411 | 0.82 | LMNA (0.47) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 | |
| SCHEMBL27999433 | 0.82 | RORC (0.42) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 | |
| SCHEMBL29359445 | 0.81 | CYP2C9 (0.65) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 | |
| SCHEMBL9940373 | 0.81 | GABRA1 (0.41) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 | |
| SCHEMBL26591 | 0.81 | CYP2C9 (0.65) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 | |
| SCHEMBL29368497 | 0.81 | CYP2C9 (0.65) | CYP2D6CYP2C9ALOX15CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11681227-B2 | Enhanced EUV photoresist materials, formulations and processes | IRRESISTIBLE MATERIALS LTD (GB) | 2023-06-20 | — | — | US | disclosed |