SCHEMBL11347484

SCHEMBL11347484

CCCCN1c2ccccc2CC1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.51
CHRM2 P08172 1/20 0.50
CHRM4 P08173 1/20 0.50
CHRM1 P11229 1/20 0.50
CHRM3 P20309 1/20 0.50
NOTUM Q6P988 1/20 0.45
ALDH1A1 P00352 3/20 0.45
GAA P10253 2/20 0.45
KDM4E B2RXH2 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
PRKCG P05129 1/20 0.44
PRKCB P05771 1/20 0.44
PRKCA P17252 1/20 0.44
PRKCH P24723 1/20 0.44
PRKCE Q02156 1/20 0.44
PRKCQ Q04759 1/20 0.44
PRKCD Q05655 1/20 0.44
KMT2A Q03164 3/20 0.44
MAPK1 P28482 1/20 0.44
MAPT P10636 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11995384 0.90 CHRM2 (0.52) PKMCHRM2CHRM4CHRM1CHRM3
SCHEMBL2632947 0.90 CHRM2 (0.52) PKMCHRM2CHRM4CHRM1CHRM3
SCHEMBL11344406 0.84 ALDH1A1 (0.44) PKMCHRM2CHRM4CHRM1CHRM3
SCHEMBL8366931 0.82 CHRM2 (0.59) PKMCHRM2CHRM4CHRM1CHRM3
SCHEMBL11346041 0.81 CHRM2 (0.55) CHRM2CHRM4CHRM1CHRM3NOTUM
SCHEMBL11354691 0.81 CHRM2 (0.51) CHRM2CHRM4CHRM1CHRM3NOTUM
SCHEMBL16685211 0.81 CHRM2 (0.51) CHRM2CHRM4CHRM1CHRM3NOTUM
SCHEMBL11351138 0.81 CHRM2 (0.51) CHRM2CHRM4CHRM1CHRM3NOTUM
Hydrochloric Acid SCHEMBL5367455 0.81 CHRM2 (0.57) PKMCHRM2CHRM4CHRM1CHRM3
SCHEMBL28797169 0.81 MTNR1A (0.44) PKMCHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4252716-A BLUE SHADES BAYER AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed
US-4006127-A Cationic diazacyanine dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed