Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30278482 | 0.80 | ALDH1A1 (0.42) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL11876810 | 0.79 | HSD17B10 (0.38) | ALDH1A1NPSR1SMN1; SMN2GAALMNA | |
| SCHEMBL1653137 | 0.71 | MAPT (0.40) | ALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL9117282 | 0.70 | TSHR (0.42) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL14580062 | 0.70 | TNKS (0.49) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL6137109 | 0.68 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL9410541 | 0.68 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL3447171 | 0.68 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL170140 | 0.68 | MAPK1 (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 | |
| SCHEMBL3543457 | 0.68 | TSHR (0.57) | MAPK1TSHRHPGDUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8603200-B2 | Compositions comprising combustion improvers and methods of use thereof | AFTON CHEMICAL CORPORATION (US) | 2013-12-10 | — | — | US | claimed |
| EP-2267103-A9 | Compositions comprising combustion improvers and methods of use thereof | Afton Chemical Corporation (US) | 2011-02-23 | — | — | EP | claimed |
| EP-2267103-A2 | Compositions comprising combustion improvers and methods of use thereof | Afton Chemical Corporation (US) | 2010-12-29 | — | — | EP | claimed |
| US-20100319243-A1 | COMPOSITIONS COMPRISING COMBUSTION IMPROVERS AND METHODS OF USE THEREOF | AFTON CHEMICAL CORPORATION (US) | 2010-12-23 | — | — | US | claimed |
| CN-115697989-A | Tropomyosin Receptor Kinase (TRK) degrading compounds and methods of use | 上海睿跃生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-8603200-B2 | Compositions comprising combustion improvers and methods of use thereof | AFTON CHEMICAL CORPORATION (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2267103-A9 | Compositions comprising combustion improvers and methods of use thereof | Afton Chemical Corporation (US) | 2011-02-23 | — | — | EP | disclosed |
| EP-2267103-A2 | Compositions comprising combustion improvers and methods of use thereof | Afton Chemical Corporation (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20100319243-A1 | COMPOSITIONS COMPRISING COMBUSTION IMPROVERS AND METHODS OF USE THEREOF | AFTON CHEMICAL CORPORATION (US) | 2010-12-23 | — | — | US | disclosed |
| EP-0406993-A2 | Substituted benzoxazolinone and benzoxazinone derivatives, process for their preparation and their use as agent with herbicide activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | disclosed |