Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7345710 | 0.77 | PARP1 (0.46) | MAPTALDH1A1NPSR1KDM4EMEN1 | |
| SCHEMBL3557147 | 0.76 | MAPT (0.46) | MAPTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL1051084 | 0.73 | CA12 (0.50) | MAPTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL1134767 | 0.71 | MAPK1 (0.50) | ALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL11876810 | 0.69 | HSD17B10 (0.38) | MAPTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL31326012 | 0.67 | ALDH1A1 (0.41) | MAPTALDH1A1LMNANPSR1SMN1; SMN2 | |
| SCHEMBL8015679 | 0.64 | MAPT (0.31) | MAPTALDH1A1NPSR1HTTMEN1 | |
| SCHEMBL4080987 | 0.64 | CDK4 (0.43) | ALDH1A1LMNARAB9AHTTMEN1 | |
| SCHEMBL30522768 | 0.64 | CDK4 (0.43) | ALDH1A1LMNARAB9AHTTMEN1 | |
| SCHEMBL891427 | 0.62 | SCN2A (0.50) | ALDH1A1SMN1; SMN2KDM4EHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150184184-A1 | GLUTAMATE RECEPTORS IN NUTRIENT SENSING, METABOLISM, GROWTH AND DEVELOPMENT | BALASUBRAMANIAN, SIVASUBRAMANIAN (IN) | 2015-07-02 | — | — | US | disclosed |
| US-8889950-B2 | Repression of AtGLR3.2 increases plant biomass | THE GEORGE WASHINGTON UNIVERSITY (US) | 2014-11-18 | — | — | US | disclosed |
| WO-2011049560-A1 | GLUTAMATE RECEPTORS IN NUTRIENT SENSING, METABOLISM, GROWTH AND DEVELOPMENT | THE GEORGE WASHINGTON UNIVERSITY (US) | 2011-04-28 | — | — | WO | disclosed |
| US-20090265805-A1 | Glutamate receptors in nutrient sensing, metabolism, Growth and Development | BALASUBRAMANIAN, SIVASUBRAMANIAN (IN) | 2009-10-22 | — | — | US | disclosed |