Fluazifop

Fluazifop

SCHEMBL1134799

CC(Oc1ccc(Oc2ccc(C(F)(F)F)cc2)cc1)C(=O)O.CC(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
RAB9A P51151 1/20 0.56
LIPE Q05469 15/20 0.55
MAPT P10636 2/20 0.51
NPSR1 Q6W5P4 2/20 0.51
BCHE P06276 1/20 0.51
CYP3A4 P08684 1/20 0.48
GAA P10253 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HTT P42858 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluazifop SCHEMBL29370478 0.97 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL1010239 0.97 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL1559717 0.97 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop-P SCHEMBL29370487 0.97 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL67403 0.97 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop-P SCHEMBL118853 0.97 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop-P SCHEMBL11006621 0.96 LMNA (0.60) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL9362442 0.96 LMNA (0.60) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL10513170 0.96 LMNA (0.60) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL16827270 0.94 LMNA (0.58) LMNARAB9ALIPEMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285215-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME Fasgen, Inc. (US) 2011-02-23 EP disclosed
WO-2009149066-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME FASGEN, INC. (US) 2009-12-10 WO disclosed
EP-2086943-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME Fasgen, LLC (US) 2009-08-12 EP disclosed
WO-2008057585-A1 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME FASGEN LLC (US) 2008-05-15 WO disclosed
EP-1539730-A4 NOVEL COMPUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME FASGEN INC (US) 2007-03-28 EP disclosed
WO-2007014249-A2 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME JOHNS HOPKINS UNIVERSITY (US) 2007-02-01 WO disclosed
WO-2007014247-A2 NOVEL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME JOHNS HOPKINS UNIVERSITY (US) 2007-02-01 WO disclosed
EP-1539730-A1 NOVEL COMPUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME Fasgen Inc. (US) 2005-06-15 EP disclosed
WO-2004005277-A1 NOVEL COMPUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHODS OF USE FOR SAME FASGEN, INC. (US) 2004-01-15 WO disclosed