Fluazifop

Fluazifop

SCHEMBL1010239

C[C@H](Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)C(=O)O

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.62
RAB9A P51151 1/20 0.58
LIPE Q05469 15/20 0.57
MAPT P10636 2/20 0.53
NPSR1 Q6W5P4 2/20 0.53
BCHE P06276 1/20 0.53
CYP3A4 P08684 1/20 0.50
GAA P10253 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluazifop SCHEMBL1559717 1.00 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL67403 1.00 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop-P SCHEMBL118853 1.00 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop-P SCHEMBL29370487 1.00 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL29370478 1.00 LMNA (0.62) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL10513170 0.99 LMNA (0.60) LMNARAB9ALIPEMAPTNPSR1
Fluazifop-P SCHEMBL11006621 0.99 LMNA (0.60) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL9362442 0.99 LMNA (0.60) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL1134799 0.97 LMNA (0.59) LMNARAB9ALIPEMAPTNPSR1
Fluazifop SCHEMBL16827270 0.96 LMNA (0.58) LMNARAB9ALIPEMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11285165-B2 Selective high-affinity polydentate ligands and methods of making such LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2022-03-29 US claimed
US-20210000843-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2021-01-07 US claimed
US-20190262364-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2019-08-29 US claimed
US-10292992-B2 Selective high-affinity polydentate ligands and methods of making such LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2019-05-21 US claimed
US-9884070-B2 Selective high-affinity polydentate ligands and methods of making such LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2018-02-06 US claimed
US-20180008621-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2018-01-11 US claimed
US-20180008622-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2018-01-11 US claimed
EP-2268654-B1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH UNIV CALIFORNIA (US) 2017-01-25 EP claimed
US-20110144065-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH U.S. DEPARTMENT OF ENERGY 2011-06-16 US claimed
EP-2268654-A2 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH The Regents of the University of California (US) 2011-01-05 EP claimed
WO-2009132020-A2 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-10-29 WO claimed
US-20080114168-A1 Novel esters as useful broad spectrum herbicidal compounds CORET JOEL M 2008-05-15 US claimed
WO-2006009964-A2 NOVEL ESTERS AS USEFUL HERBICIDAL COMPOUNDS CORET JOEL MARCEL (US) 2006-01-26 WO claimed
US-20050282708-A1 Novel esters as useful herbicidal compounds CORET JOEL M 2005-12-22 US claimed
US-11299745-B1 Herbicide resistance genes DOW AGROSCIENCES LLC (US) 2022-04-12 US disclosed
US-20220098610-A1 NOVEL HERBICIDE RESISTANCE GENES DOW AGROSCIENCES LLC (US) 2022-03-31 US disclosed
US-11285165-B2 Selective high-affinity polydentate ligands and methods of making such LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2022-03-29 US disclosed
EP-0426491-A2 Herbicidal, optically active or racemic substituted propionic acid derivatives, herbicide compositions containing them and process for preparing same ALKALOIDA VEGYESZETI GYAR (HU) 1991-05-08 EP disclosed
EP-0351021-A2 Herbicide mixtures SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-01-17 EP disclosed
US-4752326-A 1-arylpyrazoles, composition containing them, and herbicidal method of using them HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) 1988-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11285165-B2 Selective high-affinity polydentate ligands and methods of making such CD44, FCGR3B, FCGR2A LMNA 3558/4885RAB9A 3009/4885LIPE 3883/4885
US-20050282708-A1 Novel esters as useful herbicidal compounds NOTUM, DDT, HDHD5 LMNA 4616/4885RAB9A 1619/4885LIPE 19/4885
US-20110144065-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH CD44, FCGR3B, FCGR2A LMNA 3558/4885RAB9A 3009/4885LIPE 3883/4885
US-20180008621-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH CD44, FCGR3B, FCGR2A LMNA 3558/4885RAB9A 3009/4885LIPE 3883/4885
US-20180008622-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH CD44, FCGR3B, FCGR2A LMNA 3558/4885RAB9A 3009/4885LIPE 3883/4885
US-20080114168-A1 Novel esters as useful broad spectrum herbicidal compounds NOTUM, DDT, HDHD5 LMNA 4611/4885RAB9A 1798/4885LIPE 27/4885
US-20190262364-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH CD44, FCGR3B, FCGR2A LMNA 3558/4885RAB9A 3009/4885LIPE 3883/4885
US-20210000843-A1 SELECTIVE HIGH-AFFINITY POLYDENTATE LIGANDS AND METHODS OF MAKING SUCH CD44, FCGR3B, FCGR2A LMNA 3558/4885RAB9A 3009/4885LIPE 3883/4885
US-10292992-B2 Selective high-affinity polydentate ligands and methods of making such CD44, FCGR3B, FCGR2A LMNA 3558/4885RAB9A 3009/4885LIPE 3883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.