Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 7/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SHBG | P04278 | 1/20 | 0.44 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.44 |
| ▸ | G6PD | P11413 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11348027 | 1.00 | ESR1 (0.54) | ESR1ARESR2SRD5A2SRD5A1 | |
| SCHEMBL11515941 | 0.87 | SRD5A2 (0.65) | ESR1ARESR2SRD5A2SRD5A1 | |
| SCHEMBL8316478 | 0.82 | G6PD (0.61) | ESR1ARESR2SRD5A2SRD5A1 | |
| SCHEMBL11517173 | 0.82 | ESR1 (0.78) | ESR1ARESR2LMNASHBG | |
| SCHEMBL3362181 | 0.82 | ESR1 (0.78) | ESR1ARESR2LMNASHBG | |
| SCHEMBL14726730 | 0.76 | AR (0.71) | ESR1ARESR2SRD5A2SRD5A1 | |
| SCHEMBL13378032 | 0.76 | AR (0.71) | ESR1ARESR2SRD5A2SRD5A1 | |
| SCHEMBL11348922 | 0.74 | SRD5A2 (0.50) | ESR1ARESR2SRD5A2SRD5A1 | |
| SCHEMBL18944434 | 0.74 | CYP19A1 (0.63) | SRD5A2LMNASHBGSERPINA6G6PD | |
| SCHEMBL11517147 | 0.74 | CYP19A1 (0.63) | SRD5A2LMNASHBGSERPINA6G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004430-B1 | A PROCESS FOR THE SELECTIVE CONVERSION OF 20-METHYLPREGNA-3,5,20(21)-TRIENE-3,21-DIOL-DIACETATE TO 3-OXO-20-METHYL-PREGNA-4,20(21)-DIENE-21-YL-ACETATE | HENKEL CORPORATION (a Delaware corp.) (US) | 1981-12-23 | — | — | EP | claimed |