SCHEMBL11348278

SCHEMBL11348278

CCCC(Cl)(CC)NC(=O)Cl

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
TSHR P16473 1/20 0.32
EPHX1 P07099 1/20 0.32
FDPS P14324 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11348309 0.81 ALDH1A1 (0.34) ALDH1A1FDPS
SCHEMBL11100361 0.70
SCHEMBL11196231 0.64
SCHEMBL11093167 0.63
SCHEMBL11295576 0.62 ALDH1A1 (0.41) ALDH1A1TSHRFDPSTP53
SCHEMBL11319107 0.62
SCHEMBL8611874 0.62 TSHR (0.38) ALDH1A1TSHRFDPSTP53
SCHEMBL7170151 0.62 TSHR (0.38) ALDH1A1TSHRFDPSTP53
SCHEMBL10902351 0.62 FDPS (0.36) ALDH1A1TSHRFDPS
SCHEMBL809272 0.61 TSHR (0.41) ALDH1A1TSHRFDPSTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4297300-A Novel α-haloalkylcarbamic acid halides, and a process for the preparation of α-haloalkylcarbamic acid halides BASF AKTIENGESELLSCHAFT (DE) 1981-10-27 US disclosed