Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.60 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.56 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8345734 | 0.85 | KMT2A (0.78) | CYP1A2CYP2C19KMT2AMEN1MAPT | |
| SCHEMBL11604183 | 0.81 | ALDH1A1 (0.57) | CYP1A2CYP2C19KMT2AMEN1MAPT | |
| SCHEMBL14350895 | 0.80 | KMT2A (0.67) | CYP1A2CYP2C19KMT2AMEN1MAPT | |
| SCHEMBL9035434 | 0.79 | KMT2A (0.65) | CYP1A2CYP2C19KMT2AMEN1MAPT | |
| SCHEMBL11346238 | 0.79 | RAB9A (0.70) | KMT2AMEN1MAPTTP53KDM4E | |
| SCHEMBL11652385 | 0.78 | KMT2A (0.63) | CYP1A2CYP2C19KMT2AMEN1MAPT | |
| Hydrochloric Acid SCHEMBL9004713 | 0.78 | KMT2A (0.63) | CYP1A2CYP2C19KMT2AMEN1MAPT | |
| SCHEMBL8350552 | 0.78 | KMT2A (0.72) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL19427494 | 0.78 | RAB9A (0.73) | KMT2AMEN1MAPTALDH1A1GAA | |
| SCHEMBL6214665 | 0.77 | TP53 (0.66) | KMT2AMEN1MAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098788-A | Process for preparing quinazolines | BRISTOL-MYERS COMPANY (US) | 1978-07-04 | — | — | US | claimed |
| US-4304935-A | Production of 1-phenyl-3-cyanoureas | REXOLIN CHEMICALS AB (SE) | 1981-12-08 | — | — | US | disclosed |
| US-4098788-A | Process for preparing quinazolines | BRISTOL-MYERS COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4098788-A | Process for preparing quinazolines | BRISTOL-MYERS COMPANY (US) | 1978-07-04 | — | — | US | disclosed |