Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.81 |
| ▸ | CA4 | P22748 | 2/20 | 0.81 |
| ▸ | CA7 | P43166 | 2/20 | 0.81 |
| ▸ | CA9 | Q16790 | 2/20 | 0.81 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.81 |
| ▸ | CA3 | P07451 | 1/20 | 0.81 |
| ▸ | CA6 | P23280 | 1/20 | 0.81 |
| ▸ | CA5A | P35218 | 1/20 | 0.81 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | RECQL | P46063 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27888753 | 1.00 | CA12 (0.81) | CA12CA4CA7CA9CA14 | |
| Oxalic Acid SCHEMBL6473515 | 0.98 | CA12 (0.78) | CA12CA4CA7CA9CA14 | |
| Acetic Acid SCHEMBL7593865 | 0.92 | CA12 (0.78) | CA12CA4CA7CA9CA14 | |
| SCHEMBL29634851 | 0.90 | CA12 (1.00) | CA12CA4CA7CA9CA14 | |
| SCHEMBL233681 | 0.90 | CA12 (1.00) | CA12CA4CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL10896568 | 0.88 | ALDH1A1 (1.00) | CA12CA4CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL336183 | 0.88 | ALDH1A1 (1.00) | CA12CA4CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL180592 | 0.88 | ALDH1A1 (1.00) | CA12CA4CA7CA9CA14 | |
| SCHEMBL1684270 | 0.88 | CA12 (0.96) | CA12CA4CA7CA9CA14 | |
| Hydrochloric Acid SCHEMBL8749395 | 0.88 | ALDH1A1 (1.00) | CA12CA4CA7CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275031-A | A CUVETTE WITH REAGENT EMBEDDED IN A CLEAR POLYMER COATING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-06-23 | — | — | US | disclosed |