Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888619 | 0.81 | HMGCR (0.47) | GSRALDH1A1TSHRCYP3A4KDM4E | |
| SCHEMBL11342390 | 0.81 | TSHR (0.42) | GSRALDH1A1TSHRCYP3A4KDM4E | |
| SCHEMBL14174524 | 0.78 | GAA (0.64) | ALDH1A1TSHRHTTL3MBTL1GLA | |
| SCHEMBL11682066 | 0.78 | GSR (0.40) | GSRALDH1A1TSHRCYP3A4KDM4E | |
| SCHEMBL16270988 | 0.77 | GAA (0.48) | GSRALDH1A1TSHRCYP3A4KDM4E | |
| SCHEMBL11808400 | 0.76 | TSHR (0.55) | TSHRHTTL3MBTL1GLAGAA | |
| SCHEMBL2679600 | 0.76 | CYP3A4 (0.40) | ALDH1A1TSHRCYP3A4KDM4EL3MBTL1 | |
| SCHEMBL28300402 | 0.76 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP3A4KDM4EHTT | |
| SCHEMBL19627028 | 0.76 | GSR (0.67) | GSRALDH1A1TSHRCYP3A4SCN2A | |
| SCHEMBL5573148 | 0.76 | GSR (0.67) | GSRALDH1A1TSHRCYP3A4SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278577-A | HEAT RESISTANCE | AMERICAN CYANAMID COMPANY (US) | 1981-07-14 | — | — | US | disclosed |
| EP-0029090-A2 | Sulfon amides containing a hindered phenol; stabilized composition containing a synthetic polymer and said sulfon amides | AMERICAN CYANAMID COMPANY (US) | 1981-05-27 | — | — | EP | disclosed |