SCHEMBL888619

SCHEMBL888619

CCCCC(CC)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.47
ALDH1A1 P00352 9/20 0.44
TSHR P16473 4/20 0.44
GAA P10253 4/20 0.44
LMNA P02545 3/20 0.44
KMT2A Q03164 3/20 0.42
MAPK1 P28482 3/20 0.42
ATM Q13315 3/20 0.42
NPSR1 Q6W5P4 3/20 0.42
MEN1 O00255 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
BLM P54132 2/20 0.42
HIF1A Q16665 2/20 0.42
GMNN O75496 1/20 0.42
GABBR2 O75899 1/20 0.42
TP53 P04637 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
NFKB1 P19838 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9398396 0.83 MAPK1 (0.42) HMGCRALDH1A1TSHRGAALMNA
SCHEMBL21267977 0.83 HMGCR (0.39) HMGCRALDH1A1TSHRGAALMNA
SCHEMBL16270988 0.83 GAA (0.48) HMGCRALDH1A1TSHRGAALMNA
SCHEMBL21267976 0.82 HMGCR (0.41) HMGCRALDH1A1TSHRGAALMNA
SCHEMBL2679600 0.81 CYP3A4 (0.40) HMGCRALDH1A1TSHRGAALMNA
SCHEMBL11348391 0.81 GSR (0.51) HMGCRALDH1A1TSHRGAALMNA
SCHEMBL11808212 0.81 HMGCR (0.47) HMGCRALDH1A1TSHRGAALMNA
SCHEMBL9674260 0.81 ALDH1A1 (0.44) HMGCRALDH1A1TSHRGAALMNA
SCHEMBL9845247 0.81 ALDH1A1 (0.44) HMGCRALDH1A1TSHRGAALMNA
SCHEMBL11681110 0.80 ALDH1A1 (0.55) HMGCRALDH1A1TSHRGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10087390-B2 Lubricant additive for reducing timing chain wear VANDERBILT CHEMICALS, LLC (US) 2018-10-02 US claimed
CN-102812111-B Ultra low phosphorus lubricant compositions VANDERBILT CO R T 2014-06-04 CN claimed
US-7534747-B2 Gels that reduce soot and/or emissions from engines THE LUBRIZOL CORPORATION (US) 2009-05-19 US claimed
US-20090075853-A1 RELEASE ADDITIVE COMPOSITION FOR OIL FILTER SYSTEM AFTON CHEMICAL CORPORATION 2009-03-19 US claimed
US-7413583-B2 Emulsified fuels and engine oil synergy THE LUBRIZOL CORPORATION (US) 2008-08-19 US claimed
EP-1664250-A2 EMULSIFIED FUELS AND ENGINE OIL SYNERGY The Lubrizol Corporation (US) 2006-06-07 EP claimed
WO-2006022724-A1 GELS THAT REDUCE SOOT AND/OR EMISSIONS FROM ENGINES THE LUBRIZOL CORPORATION (US) 2006-03-02 WO claimed
WO-2005021691-A2 EMULSIFIED FUELS AND ENGINE OIL SYNERGY THE LUBRIZOL CORPORATION (US) 2005-03-10 WO claimed
US-20050039381-A1 Emulsified fuels and engine oil synergy LUBRIZOL CORPORATION, THE 2005-02-24 US claimed
US-20040266631-A1 Gels that reduce soot and/or emissions from engines THE LUBRIZOL CORPORATION 2004-12-30 US claimed
EP-3873955-B1 AMINO ACID GRAFTED POLYMER WITH SOOT HANDLING PROPERTIES AFTON CHEMICAL CORP (US) 2024-12-04 EP disclosed
CN-110156920-B Graft polymers with soot handling properties 雅富顿化学公司 2023-09-08 CN disclosed
EP-3527651-B1 GRAFTED POLYMER WITH SOOT HANDLING PROPERTIES AFTON CHEMICAL CORP (US) 2022-11-23 EP disclosed
CN-110028998-B Emulsifier for use in lubricating oils 雅富顿化学公司 2022-11-18 CN disclosed
CN-110194984-B Graft polymers with smoke handling properties 雅富顿化学公司 2022-09-23 CN disclosed
US-20040266630-A1 Novel additive composition that reduces soot and/or emissions from engines THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO 2004-12-30 US disclosed
US-20040266631-A1 Gels that reduce soot and/or emissions from engines THE LUBRIZOL CORPORATION 2004-12-30 US disclosed
WO-2004113479-A1 LUBRICATING OIL COMPOSITION WITH ANTIWEAR PERFORMANCE THE LUBRIZOL CORPORATION (US) 2004-12-29 WO disclosed
US-20040259743-A1 Lubricating oil composition with antiwear performance THE LUBRIZOL CORPORATION, A CORPORATION OF THE STATE OF OHIO 2004-12-23 US disclosed
US-5476604-A Crosslinked binder of polyvinyl alcohol HEWLETT-PACKARD COMPANY (US) 1995-12-19 US disclosed