SCHEMBL1134867

SCHEMBL1134867

CN(C)C(=O)NCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
OPRM1 P35372 1/20 0.58
OPRL1 P41146 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.55
HPGD P15428 2/20 0.54
GAA P10253 1/20 0.53
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C19 P33261 1/20 0.52
ALDH1A1 P00352 3/20 0.51
MAPT P10636 1/20 0.51
RIPK1 Q13546 1/20 0.51
NPSR1 Q6W5P4 1/20 0.50
EPHX1 P07099 1/20 0.50
ALOX12 P18054 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11611701 0.88 OPRM1 (0.58) TSHROPRM1OPRL1SMN1; SMN2HPGD
SCHEMBL14964721 0.86 TSHR (0.54) TSHROPRM1OPRL1SMN1; SMN2HPGD
SCHEMBL3229771 0.85 OPRM1 (0.55) TSHROPRM1OPRL1SMN1; SMN2HPGD
SCHEMBL11565084 0.85 OPRM1 (0.55) TSHROPRM1OPRL1SMN1; SMN2HPGD
SCHEMBL17342633 0.83 ALDH1A1 (0.46) TSHROPRM1OPRL1SMN1; SMN2HPGD
SCHEMBL23686835 0.83 NPC1 (0.62) OPRM1OPRL1HPGDKMT2AMEN1
SCHEMBL4428204 0.83 KMT2A (0.66) TSHRKMT2AMEN1ALDH1A1
SCHEMBL9354299 0.83 OPRM1 (0.54) TSHROPRM1OPRL1SMN1; SMN2HPGD
SCHEMBL4508687 0.82 TSHR (0.63) TSHROPRM1OPRL1SMN1; SMN2HPGD
SCHEMBL16994790 0.82 TSHR (0.63) TSHRSMN1; SMN2HPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621560-A Thermosetting resin composition, prepreg, fiber-reinforced plastic molded article, and method for producing same 三菱化学株式会社 2022-06-14 CN claimed
CN-110637041-B Epoxy resin composition for fiber-reinforced composite material and fiber-reinforced composite material 东丽株式会社 2022-05-10 CN claimed
CN-111278886-A Thermosetting resin composition, prepreg, fiber-reinforced composite material, and method for producing same 三菱化学株式会社 2020-06-12 CN claimed
CN-110637041-A Epoxy resin composition for fiber-reinforced composite material and fiber-reinforced composite material 东丽株式会社 2019-12-31 CN claimed
CN-107573649-A A kind of fast curing prepreg epoxy-resin systems and preparation method thereof 襄阳金华联航空科技有限公司 2018-01-12 CN claimed
US-8729089-B2 Pyrido(3,2-d)pyrimidines useful for treating viral infections GILEAD SCIENCES, INC. (US) 2014-05-20 US claimed
CN-114746483-B Resin composition for sheet molding compound, molded article, and method for producing sheet molding compound DIC株式会社 2024-06-25 CN disclosed
CN-118019785-A Method for producing prepreg and prepreg 三菱化学株式会社 2024-05-10 CN disclosed
CN-112839977-B Prepreg, fiber-reinforced composite resin molded body, method for producing tubular molded body, epoxy resin composition, and tubular molded body 三菱化学株式会社 2024-02-13 CN disclosed
CN-117355563-A Self-assembled carbon fiber bundle and method for producing same, and prepreg and method for producing same 三菱化学株式会社 2024-01-05 CN disclosed
CN-117242134-A Curable resin composition 三键有限公司 2023-12-15 CN disclosed
CN-117164914-A Prepreg and fiber-reinforced composite resin molded article 三菱化学株式会社 2023-12-05 CN disclosed
CN-116981721-A Resin composition, prepreg and fiber-reinforced plastic 三菱化学株式会社 2023-10-31 CN disclosed
US-20080027093-A1 Cyclohexylalanine Derivatives as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes MERCK SHARP & DOHME LLC 2008-01-31 US disclosed
CN-1301981-C Medicinal composition containing 1,3-thiazine derivative SHIONOGI & CO (JP) 2007-02-28 CN disclosed
US-7053138-B2 Flame-proofing agents HUNTSMAN ADVANCED MATERIALS AMERICAS INC. (US) 2006-05-30 US disclosed
CN-1247553-C 2-imino-1,3-thiazine derivs. SHIONOGI & CO (JP) 2006-03-29 CN disclosed
WO-2006005559-A1 STABLE CURABLE EPOXY RESIN COMPOSITIONS AND USES THEREOF HEXION SPECIALTY CHEMICALS RESEARCH BELGIUM S.A. (BE) 2006-01-19 WO disclosed
CN-1514831-A Medicinal composition containing 1,3-thiazine derivative ��Ұ����ҩ��ʽ���� 2004-07-21 CN disclosed
CN-1387519-A 2-imino-1, 3-thiazine derivatives SHIONOGI & CO (JP) 2002-12-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080027093-A1 Cyclohexylalanine Derivatives as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes DPP4, DPP3, DPP7 TSHR 4219/4885OPRM1 3620/4885OPRL1 2004/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.