SCHEMBL1135153

SCHEMBL1135153

C=C(CC(N)(CC)CC)C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
TET2 Q6N021 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17010095 0.82 TDP1 (0.36) TDP1TET2
SCHEMBL6472718 0.82 TET2 (0.48) TET2
SCHEMBL28022073 0.78 MEN1 (0.35) TDP1
SCHEMBL17183706 0.77 TDP1 (0.36) TDP1TET2
SCHEMBL27806694 0.76 TDP1 (0.39) TDP1TET2
SCHEMBL17010197 0.76 TDP1 (0.39) TDP1TET2
SCHEMBL6234394 0.75 CYP1A2 (0.33) TDP1
SCHEMBL17010094 0.74 LMNA (0.38) TDP1
SCHEMBL3232065 0.73 TDP1 (0.41) TDP1TET2
Tert-Butylamine SCHEMBL29106638 0.71 TDP1 (0.39) TDP1TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285485-A1 CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS Merck Patent GmbH (DE) 2011-02-23 EP disclosed
WO-2009143953-A1 CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS MERCK PATENT GMBH (DE) 2009-12-03 WO disclosed