Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14837074 | 0.78 | GRM4 (0.37) | TDP1 | |
| SCHEMBL1135153 | 0.78 | TDP1 (0.36) | TDP1 | |
| SCHEMBL17183635 | 0.76 | TDP1 (0.38) | TDP1 | |
| Hydrochloric Acid SCHEMBL28109007 | 0.73 | CES2 (0.39) | MEN1ALDH1A1CYP1A2KMT2ATDP1 | |
| Chloromethane SCHEMBL9166183 | 0.73 | TSHR (0.42) | MEN1ALDH1A1CYP1A2KMT2ATDP1 | |
| SCHEMBL6263445 | 0.73 | ALDH1A1 (0.43) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL28164678 | 0.73 | ALDH1A1 (0.61) | MEN1ALDH1A1CYP1A2THRBKMT2A | |
| SCHEMBL422556 | 0.72 | — | — | |
| SCHEMBL26367110 | 0.71 | TDP1 (0.32) | TDP1 | |
| SCHEMBL167050 | 0.71 | TDP1 (0.44) | MEN1ALDH1A1CYP1A2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736236-A | Surface modification of porous base supports | MERCK PATENT GMBH | 2015-06-24 | — | — | CN | claimed |
| CN-104736236-B | The surface modification of porous matrix holder | 默克专利股份公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-104736236-A | Surface modification of porous base supports | MERCK PATENT GMBH | 2015-06-24 | — | — | CN | disclosed |