Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276244 | 1.00 | PGR (0.31) | PGRADRA2AADRA2BHTR2AHRH1 | |
| SCHEMBL3279086 | 0.85 | CHRM1 (0.34) | HTR2AHRH1 | |
| SCHEMBL25233185 | 0.85 | — | — | |
| SCHEMBL736603 | 0.82 | KDM4E (0.30) | — | |
| SCHEMBL3278035 | 0.82 | — | — | |
| SCHEMBL1135132 | 0.82 | KDM4E (0.30) | — | |
| SCHEMBL1275916 | 0.82 | — | — | |
| SCHEMBL434139 | 0.82 | — | — | |
| SCHEMBL3474068 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL10636938 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673988-B2 | Graft copolymers for ion exchange chromatography | MERCK PATENT GMBH (DE) | 2014-03-18 | — | — | US | claimed |
| EP-2310104-B1 | MIXED GRAFT POLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2017-10-18 | — | — | EP | disclosed |
| EP-2285485-B1 | CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS | MERCK PATENT GMBH (DE) | 2014-04-23 | — | — | EP | disclosed |
| US-8673988-B2 | Graft copolymers for ion exchange chromatography | MERCK PATENT GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120295992-A1 | Ce(IV)-INITIATED GRAFT POLYMERISATION ON POLYMERS CONTAINING NO HYDROXYL GROUPS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-11-22 | — | — | US | disclosed |
| US-20110136925-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-06-09 | — | — | US | disclosed |
| EP-2310104-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | Merck Patent GmbH (DE) | 2011-04-20 | — | — | EP | disclosed |
| EP-2285485-A1 | CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS | Merck Patent GmbH (DE) | 2011-02-23 | — | — | EP | disclosed |
| EP-2153877-A1 | Mixed graft polymers for ion exchange chromatography | MERCK PATENT GmbH (DE) | 2010-02-17 | — | — | EP | disclosed |
| WO-2010012358-A1 | GRAFT COPOLYMERS FOR ION EXCHANGE CHROMATOGRAPHY | MERCK PATENT GMBH (DE) | 2010-02-04 | — | — | WO | disclosed |
| WO-2009143953-A1 | CE(IV)-INITIATED GRAFT POLYMERIZATION ON POLYMERS NOT CONTAINING HYDROXYL GROUPS | MERCK PATENT GMBH (DE) | 2009-12-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295992-A1 | Ce(IV)-INITIATED GRAFT POLYMERISATION ON POLYMERS CONTAINING NO HYDROXYL GROUPS | CCR4, CES2, HLA-C | PGR 1312/4885ADRA2A 3458/4885ADRA2B 2913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.