Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11349955 | 0.91 | GBA1 (0.43) | GBA1HTTALDH1A1EGFRSMN1; SMN2 | |
| SCHEMBL11351528 | 0.86 | RAB9A (0.40) | HTTALDH1A1EGFRSMN1; SMN2LMNA | |
| SCHEMBL11351291 | 0.85 | GBA1 (0.47) | GBA1HTTALDH1A1EGFRSMN1; SMN2 | |
| SCHEMBL11287542 | 0.80 | NPSR1 (0.39) | HTTALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11013925 | 0.79 | HTT (0.61) | HTTALDH1A1EGFRSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8375173 | 0.78 | HTT (0.59) | HTTALDH1A1EGFRSMN1; SMN2LMNA | |
| SCHEMBL11343481 | 0.76 | GBA1 (0.41) | GBA1HTTALDH1A1EGFRSMN1; SMN2 | |
| SCHEMBL11353852 | 0.75 | MAPT (0.44) | HTTALDH1A1EGFRSMN1; SMN2LMNA | |
| SCHEMBL11352519 | 0.75 | HTR1B (0.41) | GBA1HTTALDH1A1EGFRSMN1; SMN2 | |
| SCHEMBL11674533 | 0.74 | DRD2 (0.47) | HTTALDH1A1SMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304778-A | 4-Aminoquinazoline derivatives having fungicidal, anti-insect and acaricidal properties | SANKYO COMPANY LIMITED (JP) | 1981-12-08 | — | — | US | disclosed |