Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | IL1RN | P18510 | 1/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352163 | 0.80 | KDM1A (0.42) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11358755 | 0.80 | ADRA1A (0.34) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11352780 | 0.80 | HTR2A (0.44) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11352206 | 0.80 | ADRA1A (0.34) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11362275 | 0.80 | CA1 (0.37) | CA1CA2CA12CA7CA14 | |
| SCHEMBL29181797 | 0.80 | DRD2 (0.43) | CA1CA2CA12CA7CA14 | |
| SCHEMBL31324610 | 0.75 | DRD2 (0.46) | CA1CA2CA12CA7CA14 | |
| SCHEMBL11444214 | 0.75 | DRD2 (0.46) | CA1CA2CA12CA7CA14 | |
| SCHEMBL22092917 | 0.67 | FYN (0.56) | CA1CA2CA12CA7CA14 | |
| SCHEMBL10615264 | 0.67 | KDM4E (0.40) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001002-B1 | INDANAMINES, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-08-12 | — | — | EP | disclosed |
| EP-0001002-A1 | Indanamines, processes for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-03-07 | — | — | EP | disclosed |
| US-4128666-A | PHENYLETHANOLAMINE N-METHYL-TRANSFERASE INHIBITORS | SMITHKLINE CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |