Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234413 | 0.82 | PBRM1 (0.57) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL28052776 | 0.79 | MAPT (0.48) | F2PRSS1PRSS3MAOAMEN1 | |
| SCHEMBL329591 | 0.78 | ALDH1A1 (0.50) | F2MEN1KMT2AGAACYP3A4 | |
| SCHEMBL23480192 | 0.77 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL31650871 | 0.77 | F2 (0.59) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL16597753 | 0.77 | PBRM1 (0.63) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL1091579 | 0.77 | F2 (0.59) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL15294302 | 0.76 | TP53 (0.43) | PBRM1KMT2ACYP3A4ALDH1A1GFER | |
| SCHEMBL8712041 | 0.76 | F2 (0.52) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL27875154 | 0.75 | MAPT (0.48) | F2MEN1KMT2AGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4286045-A | A SUPPORT HAVING A LAYER OF A CHALCOGENIDE OF GERMANIUM DOPED WITH SILVER OR COPPER; STABILITY; LITHOGRAPHIC PRINTING PLATES | FUJI PHOTO FILM CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4198237-A | GERMANIUM SULFIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1980-04-15 | — | — | US | disclosed |