Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.63 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23480192 | 0.81 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL11352289 | 0.77 | PBRM1 (0.59) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL15209808 | 0.77 | PBRM1 (0.70) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL28231735 | 0.77 | PBRM1 (0.70) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL147608 | 0.77 | PBRM1 (1.00) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL16396188 | 0.77 | PBRM1 (0.59) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL1446678 | 0.77 | TSHR (0.53) | F2PRSS1PRSS3MAOACYP3A4 | |
| 3-Aminobenzoic Acid SCHEMBL27648 | 0.76 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| 3-Aminobenzoic Acid SCHEMBL8003706 | 0.76 | PBRM1 (0.69) | PBRM1F2PLGPRSS1PRSS2 | |
| SCHEMBL11234413 | 0.76 | PBRM1 (0.57) | PBRM1F2PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052512-A1 | PHOSPHORODIAMIDATE BACKBONE LINKAGE FOR OLIGONUCLEOTIDES | Geron Corporation (US) | 2016-08-10 | — | — | EP | disclosed |
| WO-2015048558-A1 | PHOSPHORODIAMIDATE BACKBONE LINKAGE FOR OLIGONUCLEOTIDES | GERON CORPORATION (US) | 2015-04-02 | — | — | WO | disclosed |