Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11368205 | 0.84 | POLB (0.62) | ALDH1A1POLBTP53BP1HRH3NPC1 | |
| SCHEMBL3243689 | 0.81 | ALDH1A1 (0.68) | ALDH1A1POLBTP53BP1NPC1RAB9A | |
| SCHEMBL11623180 | 0.81 | ALDH1A1 (0.54) | ALDH1A1POLBTP53BP1HRH3NPC1 | |
| SCHEMBL10462319 | 0.81 | AKR1C3 (0.50) | ALDH1A1POLBNPSR1CYP2C9CYP2C19 | |
| SCHEMBL11481078 | 0.79 | ALDH1A1 (0.62) | ALDH1A1POLBTP53BP1HRH3NPC1 | |
| SCHEMBL28063257 | 0.78 | MAPT (0.64) | ALDH1A1POLBHRH3NPC1RAB9A | |
| SCHEMBL701131 | 0.77 | ALDH1A1 (0.61) | ALDH1A1POLBNPSR1MEN1HTT | |
| SCHEMBL6360091 | 0.77 | POLB (1.00) | ALDH1A1POLBTP53BP1HDAC3HDAC1 | |
| SCHEMBL8029023 | 0.77 | HDAC3 (0.60) | ALDH1A1POLBTP53BP1HDAC3HDAC1 | |
| SCHEMBL11365241 | 0.76 | MAPT (0.63) | ALDH1A1POLBNPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278680-A | Hypoglycaemically and hypolipidaemically active derivatives of phenylacetic acid | BOEHRINGER MANNHEIM GMBH (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4207341-A | Hypoglycaemically and hypolipidaemically active derivatives of phenylacetic acid | BOEHRINGER-MANNHEIM GMBH (DE) | 1980-06-10 | — | — | US | disclosed |