Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | ESRRG | P62508 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481078 | 0.90 | ALDH1A1 (0.62) | POLBALDH1A1TP53BP1HDAC3HDAC4 | |
| SCHEMBL3243689 | 0.90 | ALDH1A1 (0.68) | POLBALDH1A1TP53BP1HDAC3HDAC4 | |
| SCHEMBL11353085 | 0.84 | ALDH1A1 (0.61) | POLBALDH1A1TP53BP1HDAC3HDAC1 | |
| SCHEMBL3233030 | 0.82 | NAMPT (0.64) | POLBALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL5969299 | 0.81 | ESRRG (0.73) | HDAC2HDAC8HDAC6ESRRGNPC1 | |
| SCHEMBL11357235 | 0.81 | ESRRG (0.68) | ALDH1A1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28063257 | 0.79 | MAPT (0.64) | POLBALDH1A1NPC1RAB9AHRH3 | |
| SCHEMBL613062 | 0.78 | POLB (0.67) | POLBALDH1A1TP53BP1LMNATP53 | |
| SCHEMBL30407428 | 0.78 | POLB (0.67) | POLBALDH1A1TP53BP1LMNATP53 | |
| SCHEMBL3514277 | 0.78 | POLB (0.76) | POLBALDH1A1TP53BP1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278680-A | Hypoglycaemically and hypolipidaemically active derivatives of phenylacetic acid | BOEHRINGER MANNHEIM GMBH (DE) | 1981-07-14 | — | — | US | disclosed |
| US-4207341-A | Hypoglycaemically and hypolipidaemically active derivatives of phenylacetic acid | BOEHRINGER-MANNHEIM GMBH (DE) | 1980-06-10 | — | — | US | disclosed |