Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404416 | 0.85 | CA12 (0.49) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL186606 | 0.82 | CA12 (0.43) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29956354 | 0.82 | MCHR1 (0.44) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL472526 | 0.81 | GAA (0.43) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31106597 | 0.81 | MCHR1 (0.47) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31106589 | 0.81 | MCHR1 (0.47) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30828010 | 0.81 | ALDH1A1 (0.43) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2559136 | 0.78 | CA2 (0.44) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29950734 | 0.78 | GAA (0.41) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10957173 | 0.77 | ALDH1A1 (0.41) | GAAALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4303786-A | Isonitrile derivatives of macromolecules containing hydroxyl groups | RAMOT - TEL-AVIV UNIVERSITY (IL) | 1981-12-01 | — | — | US | disclosed |