Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352759 | 0.81 | KDM4E (0.48) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL30148104 | 0.65 | ABCB1 (0.50) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11355122 | 0.65 | KDM4E (0.51) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL4160835 | 0.64 | KDM4E (1.00) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL10851137 | 0.64 | HTR5A (0.40) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11192598 | 0.64 | HSD17B10 (0.54) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL11174540 | 0.64 | TP53 (0.39) | KDM4EMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL11112201 | 0.63 | HTR5A (0.39) | KDM4EMEN1KMT2AMAPTABCB1 | |
| SCHEMBL4153685 | 0.63 | KDM4E (0.76) | KDM4EGAAMEN1KMT2AALDH1A1 | |
| SCHEMBL10851703 | 0.63 | ABCB1 (0.41) | KDM4EGAAALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277476-A | ANTI-ANOXIA AND PSYCHOTROPIC AGENTS | SYNTHELABO (FR) | 1981-07-07 | — | — | US | disclosed |