SCHEMBL11354557

SCHEMBL11354557

CCCCc1ccc(OP(O)O)c(CCCCCCCCCc2ccccc2)c1CCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.40
CYSLTR2 Q9NS75 1/20 0.38
CYSLTR1 Q9Y271 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
TRPV1 Q8NER1 1/20 0.36
TLR8 Q9NR97 1/20 0.36
TLR7 Q9NYK1 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
ESR1 P03372 2/20 0.36
ADRA2A P08913 2/20 0.36
ADORA3 P0DMS8 2/20 0.36
TACR2 P21452 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
SHBG P04278 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130578 0.88 TYR (0.44) LIPGALDH1A1TP53CYP3A4PTGS2
SCHEMBL10883586 0.88 TYR (0.44) LIPGALDH1A1TP53CYP3A4PTGS2
SCHEMBL8047086 0.88 TYR (0.44) LIPGALDH1A1TP53CYP3A4PTGS2
SCHEMBL29358468 0.88 TYR (0.44) LIPGALDH1A1TP53CYP3A4PTGS2
SCHEMBL10790741 0.88 TYR (0.44) LIPGALDH1A1TP53CYP3A4PTGS2
SCHEMBL443621 0.88 TYR (0.39) LIPGKDM4EALDH1A1LMNATP53
SCHEMBL7074311 0.86 TYR (0.43) LIPGALDH1A1TP53CYP3A4PTGS2
SCHEMBL11033803 0.85 THRA (0.38) CYSLTR2CYSLTR1LIPGKDM4EALDH1A1
SCHEMBL991306 0.80 TYR (0.38) LIPGALDH1A1TP53CYP3A4PTGS2
SCHEMBL28429633 0.80 LIPG (0.39) CYSLTR2CYSLTR1LIPGKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4285833-A Catalyst, its production and a process for the polymerization of butadiene BAYER AKTIENGESELLSCHAFT (DE) 1981-08-25 US disclosed