Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.59 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11352715 | 0.81 | MAPKAPK2 (0.55) | ADRA1AADRA1DKDM4EDRD2DRD1 | |
| SCHEMBL30363084 | 0.81 | CHRNA7 (0.67) | CHRNA7ADRA1AADRA1DADRA1BKDM4E | |
| SCHEMBL2887057 | 0.81 | CHRNA7 (0.67) | CHRNA7ADRA1AADRA1DADRA1BKDM4E | |
| SCHEMBL30363160 | 0.81 | CHRNA7 (0.67) | CHRNA7ADRA1AADRA1DADRA1BKDM4E | |
| Desbromoarborescidine A SCHEMBL31662855 | 0.80 | CHRNA7 (0.66) | CHRNA7ADRA1AADRA1DADRA1BADRA2A | |
| Desbromoarborescidine A SCHEMBL30363173 | 0.80 | CHRNA7 (0.66) | CHRNA7ADRA1AADRA1DADRA1BADRA2A | |
| Desbromoarborescidine A SCHEMBL29002756 | 0.80 | CHRNA7 (0.66) | CHRNA7ADRA1AADRA1DADRA1BADRA2A | |
| Desbromoarborescidine A SCHEMBL5269957 | 0.80 | CHRNA7 (0.66) | CHRNA7ADRA1AADRA1DADRA1BADRA2A | |
| SCHEMBL11352593 | 0.79 | ADRA1D (0.53) | CHRNA7ADRA1AADRA1DADRA1BKDM4E | |
| SCHEMBL29458059 | 0.78 | CHRNA7 (0.64) | CHRNA7ADRA1AADRA1DADRA1BADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277476-A | ANTI-ANOXIA AND PSYCHOTROPIC AGENTS | SYNTHELABO (FR) | 1981-07-07 | — | — | US | disclosed |