Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351416 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TDP1CYP2D6L3MBTL1MEN1 | |
| SCHEMBL11495109 | 0.91 | ALDH1A1 (0.38) | ALDH1A1TDP1L3MBTL1MAPTMEN1 | |
| SCHEMBL11492087 | 0.91 | ALDH1A1 (0.36) | ALDH1A1TDP1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11354941 | 0.85 | ALDH1A1 (0.39) | ALDH1A1TDP1L3MBTL1MAPTMAP4K4 | |
| SCHEMBL11505296 | 0.83 | TDP1 (0.59) | ALDH1A1TDP1CYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL9789540 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TDP1 | |
| SCHEMBL11492578 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TDP1CYP2D6L3MBTL1MEN1 | |
| SCHEMBL11271091 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1L3MBTL1ATM | |
| SCHEMBL11402704 | 0.76 | AKR1C3 (0.37) | ALDH1A1TDP1GAAKMT2APLA2G10 | |
| SCHEMBL11365298 | 0.75 | TDP1 (0.62) | ALDH1A1TDP1L3MBTL1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221799-A | MITICIDES | THE DOW CHEMICAL (US) | 1980-09-09 | — | — | US | claimed |
| US-4258048-A | Substituted pyridine methyl esters of tetramethyl cyclopropane carboxylic acids and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1981-03-24 | — | — | US | disclosed |
| US-4221799-A | MITICIDES | THE DOW CHEMICAL (US) | 1980-09-09 | — | — | US | disclosed |