Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11351416 | 0.90 | ALDH1A1 (0.44) | ALDH1A1TDP1HSD17B14 | |
| SCHEMBL11492087 | 0.83 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL11355103 | 0.82 | ALDH1A1 (0.37) | ALDH1A1TDP1 | |
| SCHEMBL11354941 | 0.81 | ALDH1A1 (0.39) | ALDH1A1TDP1 | |
| SCHEMBL11495109 | 0.81 | ALDH1A1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL11271091 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1HSD17B14 | |
| SCHEMBL11492578 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TDP1HSD17B14 | |
| SCHEMBL29391915 | 0.77 | TDP1 (0.69) | ALDH1A1TDP1 | |
| SCHEMBL11268455 | 0.77 | TDP1 (0.69) | ALDH1A1TDP1 | |
| SCHEMBL11270951 | 0.77 | TDP1 (0.69) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049585-A | Certain 3,3-bis-(difluoro methyl)2,2-dimethyl-cyclopropane carboxylates having insecticidal activity | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-17 | — | — | US | disclosed |