SCHEMBL11355232

SCHEMBL11355232

C=C[Si](C)(C)c1ccc(C(=O)Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
HPGD P15428 2/20 0.39
ALDH1A1 P00352 1/20 0.37
ALDH5A1 P51649 1/20 0.31
ABAT P80404 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11351398 0.81 HPGD (0.59) NR1H2NR1H3HPGDALDH1A1
SCHEMBL11744172 0.80 SRD5A2 (0.48) NR1H2NR1H3HPGD
Potassium Ion SCHEMBL11351388 0.79 NR1H2 (0.46) NR1H2NR1H3HPGD
SCHEMBL678612 0.78 NR1H2 (0.59) NR1H2NR1H3
SCHEMBL11746059 0.78 ALDH1A1 (0.57) NR1H2NR1H3HPGDALDH1A1THRB
SCHEMBL9716978 0.77 HPGD (0.46) NR1H2NR1H3HPGDALDH1A1
SCHEMBL8413865 0.77 HPGD (0.64) NR1H2NR1H3HPGDALDH1A1
SCHEMBL9651755 0.76 NR1H2 (0.50) NR1H2NR1H3HPGD
SCHEMBL9331875 0.75 HPGD (0.45) HPGDALDH1A1
SCHEMBL10789745 0.75 HPGD (0.45) HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4301231-A SOLUBLE FILM FORMING POLYMER CONTAINING VINYL SILYL BRANCHES TORAY INDUSTRIES, INCORPORATED (JP) 1981-11-17 US disclosed