Saccharin

Saccharin

SCHEMBL11355404

NC(N)=O.O=C1NS(=O)(=O)c2ccccc21

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 0.85
CA9 Q16790 8/20 0.85
CA2 P00918 7/20 0.85
CA1 P00915 4/20 0.85
CA7 P43166 3/20 0.85
KDM4E B2RXH2 2/20 0.85
KMT2A Q03164 2/20 0.85
CA4 P22748 2/20 0.85
USP2 O75604 1/20 0.85
LMNA P02545 1/20 0.85
BCHE P06276 1/20 0.85
CA6 P23280 1/20 0.85
CA5A P35218 1/20 0.85
CA14 Q9ULX7 1/20 0.85
CA5B Q9Y2D0 1/20 0.85
ALDH1A1 P00352 2/20 0.54
HSD11B1 P28845 1/20 0.50
RET P07949 2/20 0.49
GRK5 P34947 2/20 0.49
TYRO3 Q06418 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Saccharin SCHEMBL28167143 0.94 CA12 (0.81) CA12CA9CA2CA1CA7
Saccharin SCHEMBL5137729 0.94 CA12 (0.81) CA12CA9CA2CA1CA7
Saccharin SCHEMBL11600574 0.93 CA12 (0.79) CA12CA9CA2CA1CA7
Saccharin SCHEMBL28134145 0.92 CA12 (0.92) CA12CA9CA2CA1CA7
Saccharin SCHEMBL29037506 0.92 CA12 (0.92) CA12CA9CA2CA1CA7
Saccharin SCHEMBL28045129 0.92 CA12 (0.92) CA12CA9CA2CA1CA7
Saccharin SCHEMBL3816 0.92 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL7073018 0.92 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL29191365 0.92 CA12 (1.00) CA12CA9CA2CA1CA7
Saccharin SCHEMBL6033672 0.92 CA12 (1.00) CA12CA9CA2CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1403153-A Water dispersive nano level bone morphogenetic protein injection prepn and its prepn process UNIV ZHEJIANG (CN) 2003-03-19 CN claimed
CN-116062787-A Method for preparing nano metal oxide by thickening method 武汉工程大学 2023-05-05 CN disclosed
CN-110137462-B Preparation method of lithium sulfide/carbon composite material for aluminum/lithium sulfide battery 浙江大学 2021-07-23 CN disclosed
CN-110137462-A Preparation method for aluminium/lithium sulphide battery vulcanization lithium/carbon composite material 浙江大学 2019-08-16 CN disclosed
US-4251403-A POLYVINYL ALCOHOL E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-02-17 US disclosed