SCHEMBL113557

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL111889	0.88	CXCR3 (0.67)	CXCR3KCNH2MAPTKMT2ASMN1; SMN2
	SCHEMBL114642	0.87	CXCR3 (0.58)	CXCR3KCNH2HTTMAPK1MAPT
	SCHEMBL111560	0.85	CXCR3 (0.56)	CXCR3KCNH2MAPK1MAPTKMT2A
	SCHEMBL111162	0.85	CXCR3 (0.54)	CXCR3KCNH2HTTMAPK1MAPT
	SCHEMBL110135	0.85	LMNA (0.60)	CXCR3KCNH2HTTMAPTKMT2A
	SCHEMBL112584	0.85	CXCR3 (0.55)	CXCR3KCNH2HTTMAPK1KMT2A
	SCHEMBL110498	0.84	CXCR3 (0.59)	CXCR3KCNH2MAPK1MAPTKMT2A
	SCHEMBL111833	0.84	CXCR3 (0.61)	CXCR3KCNH2MAPTKMT2ASMN1; SMN2
	SCHEMBL110415	0.83	CXCR3 (0.58)	CXCR3KCNH2HTTKMT2ASMN1; SMN2
	SCHEMBL111356	0.83	CXCR3 (0.53)	CXCR3KCNH2MAPK1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.