Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.56 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10629700 | 0.84 | MAPT (0.62) | MEN1KMT2ANR1H4CA1CA2 | |
| SCHEMBL10864497 | 0.83 | MEN1 (0.59) | MEN1KMT2ANR1H4CA2GAA | |
| SCHEMBL7231673 | 0.81 | GAA (0.61) | MEN1KMT2ANR1H4CA1CA2 | |
| SCHEMBL9250647 | 0.81 | ALDH1A1 (0.61) | MEN1KMT2ANR1H4GAAPOLB | |
| SCHEMBL13290702 | 0.81 | EPHX2 (0.79) | MEN1KMT2ANR1H4CA1CA2 | |
| SCHEMBL14271185 | 0.81 | NR1H4 (0.60) | MEN1KMT2ANR1H4GAAPOLB | |
| SCHEMBL8689095 | 0.81 | MEN1 (0.62) | MEN1KMT2ANR1H4GAAPOLB | |
| SCHEMBL19154569 | 0.81 | CA1 (0.58) | MEN1KMT2ALTA4HCA1CA2 | |
| SCHEMBL13849278 | 0.81 | MEN1 (0.61) | MEN1KMT2ANR1H4CA2GAA | |
| SCHEMBL10457090 | 0.80 | MEN1 (0.65) | MEN1KMT2ANR1H4CA2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297489-A | CEPHALOSPORINS | BRISTOL-MYERS COMPANY (US) | 1981-10-27 | — | — | US | disclosed |