Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15267699 | 0.84 | KMT2A (0.60) | MEN1KMT2AGAAPOLBKDM4E | |
| SCHEMBL10864497 | 0.83 | MEN1 (0.59) | MEN1KMT2ANR1H4GAAPOLB | |
| SCHEMBL9250647 | 0.81 | ALDH1A1 (0.61) | MEN1KMT2ANR1H4GAAPOLB | |
| SCHEMBL7231673 | 0.81 | GAA (0.61) | MEN1KMT2ANR1H4GAAPOLB | |
| SCHEMBL14271185 | 0.81 | NR1H4 (0.60) | MEN1KMT2ANR1H4GAAPOLB | |
| SCHEMBL13290702 | 0.81 | EPHX2 (0.79) | MEN1KMT2ANR1H4GAAKDM4E | |
| SCHEMBL11355706 | 0.81 | MEN1 (0.57) | MEN1KMT2ANR1H4GAAPOLB | |
| SCHEMBL8667875 | 0.81 | KMT2A (0.48) | MEN1KMT2AGAAPOLBEPHX2 | |
| SCHEMBL4787002 | 0.81 | KMT2A (0.51) | MEN1KMT2AGAAPOLBEPHX2 | |
| SCHEMBL19889056 | 0.81 | SMN1; SMN2 (0.58) | MEN1KMT2AKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952297-B | Compound (I) | 奥斯陆大学 | 2022-02-25 | — | — | CN | disclosed |
| US-5741926-A | ANTIDIABETIC AGENT | SHAMAN PHARMACEUTICALS, INC. (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1997030019-A1 | ANILINE DERIVATIVES HAVING ANTIHYPERGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1997-08-21 | — | — | WO | disclosed |