Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 3/20 | 0.50 |
| ▸ | ACE | P12821 | 3/20 | 0.50 |
| ▸ | CPA1 | P15085 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11122263 | 0.94 | CA1 (0.57) | CA1CA2FOLH1HPGDSITGB1 | |
| SCHEMBL11122142 | 0.94 | CA1 (0.57) | CA1CA2FOLH1HPGDSITGB1 | |
| SCHEMBL11352264 | 0.82 | FOLH1 (0.54) | CA1CA2FOLH1ITGB1ITGA4 | |
| SCHEMBL11345537 | 0.82 | CA2 (0.60) | CA1CA2FOLH1MMEACE | |
| SCHEMBL8895300 | 0.80 | FOLH1 (0.53) | CA1CA2FOLH1ALDH1A1GFER | |
| SCHEMBL31099238 | 0.80 | CA1 (0.57) | CA1CA2FOLH1ITGB1ITGA4 | |
| SCHEMBL11348583 | 0.80 | ITGB1 (0.57) | CA1CA2FOLH1ITGB1ITGA4 | |
| SCHEMBL11119910 | 0.79 | CA1 (0.56) | CA1CA2FOLH1HPGDSITGB1 | |
| SCHEMBL2545591 | 0.77 | ACE (0.65) | FOLH1MMEACECPA1ACE2 | |
| SCHEMBL2493049 | 0.77 | ACE (0.65) | FOLH1MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4302448-A | Secretin preparations with intensified and protracted action, process for their manufacture, their use as well as dihydroxybenzoyl-L-tyrosine | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-11-24 | — | — | US | disclosed |