SCHEMBL11355997

SCHEMBL11355997

CCC(NC(=O)c1ccc(C(=O)c2ccccc2)cc1)N(C)C

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.66
ALDH1A1 P00352 5/20 0.66
SMN1; SMN2 Q16637 2/20 0.52
HPGD P15428 6/20 0.47
NPC1 O15118 3/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
PRSS1 P07477 1/20 0.46
CTSG P08311 1/20 0.46
CTRB1 P17538 1/20 0.46
CMA1 P23946 1/20 0.46
CNR2 P34972 1/20 0.46
LMNA P02545 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
HTT P42858 2/20 0.43
FFAR1 O14842 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10147900 0.94 ALDH1A1 (0.55) RAB9AALDH1A1SMN1; SMN2HPGDNPC1
SCHEMBL27709158 0.80 ALDH1A1 (0.47) RAB9AALDH1A1SMN1; SMN2HPGDMEN1
SCHEMBL10718771 0.77 RAB9A (0.53) RAB9AALDH1A1SMN1; SMN2NPC1MEN1
SCHEMBL13753392 0.75 ALDH1A1 (0.70) RAB9AALDH1A1SMN1; SMN2HPGDNPC1
SCHEMBL403934 0.75 RAB9A (0.64) RAB9AALDH1A1SMN1; SMN2HPGDNPC1
SCHEMBL13441952 0.74 RAB9A (0.67) RAB9AALDH1A1SMN1; SMN2HPGDNPC1
SCHEMBL15146792 0.73 HTT (0.68) RAB9AALDH1A1SMN1; SMN2HPGDNPC1
SCHEMBL11357069 0.73 RAB9A (0.62) RAB9AALDH1A1SMN1; SMN2HPGDNPC1
SCHEMBL4797796 0.73 RAB9A (0.62) RAB9AALDH1A1HPGDNPC1MEN1
SCHEMBL11362315 0.72 RAB9A (0.66) RAB9AALDH1A1SMN1; SMN2HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0000705-B1 USE OF ESTERS OR AMIDES OF BENZOYLBENZOIC ACIDS AS PHOTOINITIATORS AND PHOTOPOLYMERISABLE COMPOSITION CONTAINING THEM STAUFFER CHEMICAL COMPANY (US) 1981-02-11 EP disclosed
EP-0000705-A1 Use of esters or amides of benzoylbenzoic acids as photoinitiators and photopolymerisable composition containing them STAUFFER CHEMICAL COMPANY (US) 1979-02-21 EP disclosed
US-4080275-A POLYMERIZATION INITIATOR, ETHYLENICALLY UNSATURATED MONOMER STAUFFER CHEMICAL COMPANY (US) 1978-03-21 US disclosed