Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31405188 | 1.00 | HSP90AA1 (0.77) | HSP90AA1TSHRLMNAALDH1A1ACHE | |
| SCHEMBL2887765 | 0.94 | HSP90AA1 (0.69) | HSP90AA1TSHRLMNAALDH1A1ACHE | |
| SCHEMBL4801505 | 0.89 | TSHR (0.70) | HSP90AA1TSHRLMNAALDH1A1ACHE | |
| SCHEMBL18550254 | 0.88 | HSP90AA1 (0.61) | HSP90AA1TSHRLMNAALDH1A1ACHE | |
| SCHEMBL20591230 | 0.88 | HSP90AA1 (0.61) | HSP90AA1TSHRLMNAALDH1A1ACHE | |
| SCHEMBL20347051 | 0.87 | HSP90AA1 (0.77) | HSP90AA1TSHRLMNAALDH1A1ACHE | |
| SCHEMBL31482901 | 0.87 | HSP90AA1 (1.00) | HSP90AA1TSHRLMNAALDH1A1ACHE | |
| SCHEMBL30468119 | 0.87 | HSP90AA1 (1.00) | HSP90AA1TSHRLMNAALDH1A1ACHE | |
| SCHEMBL288227 | 0.87 | HSP90AA1 (1.00) | HSP90AA1TSHRLMNAALDH1A1ACHE | |
| SCHEMBL1818188 | 0.85 | HSP90AA1 (0.74) | HSP90AA1TSHRLMNAALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999149-B | Preparation method for synthesizing diaryl sulfide compound based on L-cysteine | 沈阳药科大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-113166046-B | Diamine compound, polyimide precursor using same, and polyimide film | 株式会社LG化学 | 2023-06-06 | — | — | CN | disclosed |
| CN-113999149-A | Preparation method for synthesizing diaryl thioether compound based on L-cysteine | 沈阳药科大学 | 2022-02-01 | — | — | CN | disclosed |
| CN-103787802-B | One class arylalkyl thioethers compound and synthetic method thereof | EAST CHINA NORMAL UNIVERSITY (CN) | 2015-08-19 | — | — | CN | disclosed |
| CN-104725172-A | Synthetic method of aryl sulfide type compound | UNIV EAST CHINA NORMAL | 2015-06-24 | — | — | CN | disclosed |
| CN-104045589-A | Aryl alkyl thioether compound and synthetic method thereof | UNIV EAST CHINA NORMAL | 2014-09-17 | — | — | CN | disclosed |
| CN-103848767-A | Synthetic method of aryl thioether compound | UNIV EAST CHINA NORMAL | 2014-06-11 | — | — | CN | disclosed |
| CN-103787802-A | Aryl alkyl thioether compounds and synthesis method thereof | UNIV EAST CHINA NORMAL | 2014-05-14 | — | — | CN | disclosed |
| US-4286964-A | Polyfunctional epoxides and halohydrins used as bridging groups to bind aromatic amine group-containing alcohols and thiols to hydroxyl bearing substrates | SEED BRIAN S | 1981-09-01 | — | — | US | disclosed |
| EP-0027377-A1 | Derivatives of hydroxyl-bearing substrates, process for their preparation and a method of application | Seed, Brian Sarsfield (US) | 1981-04-22 | — | — | EP | disclosed |
| US-4238619-A | Method for making aryl onium salts of group via elements | GENERAL ELECTRIC COMPANY (US) | 1980-12-09 | — | — | US | disclosed |